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Nano4CRISPR: Novel nanocarrier reagents for environmental delivery of CRISPR/Cas

Nano4CRISPR: Novel nanocarrier reagents for environmental delivery of CRISPR/Cas

Nano4CRISPR will generate knowledge on nanoparticles based CRISPR delivery products that can be applied externally to crops in the open field for both agricultural and environmental purposes. The project aims to contribute to the transition towards environmentally friendly and sustainable food production following a Responsible Research and Innovation co-creation platform. NanoCRISPR conjugates have the potential to contribute to reducing the use of harmful chemistries that create persistent agrochemical pollution and to increasing resilience and suitability of our food system. The main goal of Nano4CRISPR is to develop, test and risk assess an integrated platform for the development of personalized nanoCRISPR conjugates for use in future gene-editing products directly in the field or at point of scale. Rational nanoparticle design will enable the development of nanoCRISPR conjugates that can overcome membranes and rigid cell walls surrounding plant cells and enable gene-editing in whole plants, in the field, without the aid of complicated, long and laborious genetic engineering processes. Hence, the approach is also suitable for other field applications, such as in aquaculture, pest control, and ecological conservation purposes. The integrated gene-editing platform comprehends a holistic risk assessment approach including the investigation of unintended and malicious use. Stakeholders from academia, industry, governmental agencies, and civil society organizations in Norway and other European countries will actively participate with us in a co-creation process that delivers high societal relevance and trust.

Contact

Arinze Stanley Okoli

Senior Researcher - Tromsø

arok@norceresearch.no
+47 56 10 78 85

Project facts

Name

Nano4CRISPR: Novel nanocarrier reagents for environmental delivery of CRISPR/Cas

Status

Active

Duration

01.01.24 - 31.12.27

Location

Tromsø

Total budget

15.000.000 NOK

Research areas

Research group

Funding

Research Council of Norway (RCN)

Prosjekteier

NORCE

Project members

Philomena N Chu
Gisle Øye
Sigfrid Skjeldaas

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