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NorZymeD - Enzyme development for Norwegian biomass - mining Norwegian biodiversity for seizing Norwegian opportunities in the bio-based economy

NorZymeD - Enzyme development for Norwegian biomass - mining Norwegian biodiversity for seizing Norwegian opportunities in the bio-based economy

The basis for a national bio-economy lies in the development of a biorefining industry enabled by enzyme tools that are tailored for Norwegian biomass and business opportunities. This projcct focuses on developing enzymesand processes for biomasses and value chains where Norway has clear competitive advantages, namely lignocellulosics and marine co-products from fisheries and aquaculture. Starting at unique biodiversities of thearctic, hot vents and gut microbiomes, the project will build generic competence by establishing a national"enzyme developmcnt pipeline" . Through national complementarity and distribution of ta sks, we will combincexpertise on thermophilic enzymes in Bergen and cold-adapted enzymes in Tromsø, with expertise in enzymeengineering and applied enzymology in Ås, fermentation and screening facilities at SINTEF, and structuralcharacterization in Tromsø. We will develop generic technology competence in four work packages, focusing onmetagenomie sampling (WP I), screening and characterization of candidate enzymes (WP2,WP3), enzymeengineering (WP4) and larger-scale production for industrial trials (WP2). One innovative aim is to combinc the best of cold- and heat-adapted enzymes using bioinformatics, protein engineering and gene shuffling-baseddirected evolution. The project workflow will follow the value creation chain all the way to industrial trials. Thisis underscored by the involvement of two Norwegian companies with a strong R&D focus, which has made themleaders in lignocellulosic (WP5) and marine co-product biorcfining (WP6). By linking enzyme development intwo different value chains (blue and green), the project will unleash considerable synergies. Ethical, legal andsocietal aspects will be pursued in a dedicated work package (WP8). Expanding the interest to explorebiocatalytic opportunities will be an important task for the management group (WP7,WP9), which will interactstrongly with the Industrial Biotech Network Norway (IBNN).

Project facts

Name

NorZymeD - Enzyme development for Norwegian biomass - mining Norwegian biodiversity for seizing Norwegian opportunities in the bio-based economy

Status

CONCLUDED

Duration

01.12.12 - 30.11.17

Research group

Funding

Research Council of Norway (RCN)

Project members

Vincent Eijsink
Heidi Rudi
Bjørn Olav Steinsbu
Håvard Sletta
Anna Lewin
Anne Tøndervik
Seila Pandur
Simone Balzer Le
Marianne Slang Jensen
Marie-Josée Haglund Halsør
Lasse Fredriksen
Hasan Arsin
Bjørn Altermark
Jan Arne Vevatne
Oskar Bengtsson
Ida Helene Steen
Gustav Vaaje-Kolstad
Phillip Pope
Kristin Hals
Kjartan Sandnes
Geir Klinkenberg
Arne O. Smalås
Martin Lersch
Roger Strand
Morten Walløe Tvedt
Dorothy Jane Dankel
Runar Stokke
Ågot Aakra